Your English writing platform
Discover LudwigExact(1)
These novel channels now provide an excellent model system to determine the structural basis of subconductance levels and contribution of heteromeric pore architecture to this process.
Similar(59)
This result further demonstrates the ability of the XtKir5.1 subunit to prolong the duration of these subconductance levels upon heteromultimerisation with Kir4.0 subunits.
Furthermore, the rarity of channel subconductance levels makes their quantitative analysis difficult and time-consuming.
The individual transitions appeared to consist of several subconductance levels, which were too small to resolve.
Although the I323T currents recorded at +100 and +60 mV with 10 μM intracellular Ca2+ were very flickery, we were still able to recognize the existence of the four subconductance levels as indicated by arrowheads in Fig. 4 A. Because most of the open time durations of the mutant I323T were <1 ms, the open time intervals of each sublevel were mostly shorter than 1 ms too.
Examination of these sublevels indicates three clearly visible subconductance levels of approximately ¼, ½ and ¾ the size of the fully open level (45 pS) (Figs. 2B and 4A).
Like many other types of channels, LTCCs show multiple subconductance levels in addition to the largest and the main open state of the channel.
Activation of this dimer resulted in two subconductance levels in single-channel gating by strong depolarizations, suggesting that there was a disruption of cooperativity in it.
This channel exhibits four subconductance levels similar to those of dSlo1A.
Wei et al. (23) reported that an alternative splice variant of the dSlo family (dSlo1A) from Drosophila could have subconductance levels induced by the core.
Slight variations of conductance within those two dominating states likely represent subconductance levels, which are, however, not discussed further to maintain our focus on the major changes in conductance and pore behavior.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com