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Similarities between Human Ser/Thr phosphatase PP2Cα and the mycobacterial enzyme have been explained on the basis of structural folds, metal binding and conserved residues [18].
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Interestingly, a dendrogram generated solely on the basis of structural dissimilarity measure at the level of domain folds was found to cluster functionally similar members.
Here we investigate the molecular basis of structural diversity in mDN axonal projections.
The Minimal Structural Domain Set contains 1882 domains defined purely on the basis of structural compactness.
On the basis of structural topology, the nine main MRPs can be divided into two groups.
Cross-reactivity between penicillins and carbapenems would be expected on the basis of structural similarity.
GATA factors are classified into two subfamilies on the basis of structural features and expression patterns.
The majority of the protein structural folds lack antimicrobial activities.
Keratins (heteropolymeric structural proteins) form the basis of the structural constituent of the epidermis during epidermal development.
According to ADAM, AMP structural folds are limited, only covering about 3% of the overall protein fold space.
According to ADAM, AMP structural folds are limited AMPs only cover about 3% of the overall protein fold space.
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