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The elastic theory formed the basis of structural analysis until World War II, when bomb-damaged buildings were observed to behave in unpredicted ways and the underlying assumptions of the theory were found to require modification.
On the basis of structural analysis combined with kinetic assays, we demonstrate that the final modified product with seven sugar rings is best suited for occupying the full active site and shows the most efficient inhibition of HPA.
On the basis of structural analysis by the bond valence model, it is microscopically found that intrinsic defects in lithium niobate (LN) single crystals lead to a local contraction around NbLi4+ □Li sites (□Li means a vacant site at the original Li-site).
On the basis of structural analysis, biochemical experiments and previous studies, we propose a dynamic opening and closing mechanism for type I methyltransferase.
On the basis of structural analysis, we cannot determine whether this is a property of Mn2+ vs Mg2+ or whether the much lower resolution of the Mn2+ structure masks this type of disorder.
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But his long-term ambition is to create a computerized database recording all graphemes everywhere, classifying them geographically, chronologically and typologically on the basis of his method of structural analysis.
FALSIRE focused on evaluation of structural analysis and fracture assessment methods on the basis of experimental and analytical results.
We used the Intrex questionnaire [ 24, 25] for continuous assessment of the therapeutic interaction which was developed on the basis of the "Structural Analysis of Social Behavior" model [ 26].
On the basis of recent structural analysis of ERGIC-53, also known as LMAN1, it has been suggested that modulation of binding by different Ca2+ concentrations occurs in various luminal compartments in cells [ 24 ].
On the basis of the structural analysis of these enzymes, it became clear that these enzymes, much like FIH, would require molecular oxygen and 2-oxoglutarate to catalyse their enzymatic reactions, suggesting that JmjC enzymes could act as molecular oxygen sensors in the cell.
On the basis of the structural analysis presented above, we expected that loss of contacts with Leu73 and perhaps also with Arg42 of ubiquitin with the T319 mutant may destabilize the Michaelis complex relative to the wild-type enzyme.
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