Sentence examples similar to basis of stem fate from inspiring English sources

In this paper we shall use a computational model of stem cell differentiation to explore the molecular basis of cell fate specification and reprogramming by defined factors.

Control of stem cell fate and phenotype using biomimetic synthetic extracellular matrices (ECMs) is an important tissue engineering approach.

This reprogramming of stem cell fate likely involved hedgehog and bone morphogenic protein signalling.

Cell cycle inhibitors are well known modulators of stem cell fate.

Many different pathways are involved in the determination of stem cell fate.

Therefore, Oct4 regulation might be important in determination of stem cell fate.

It is now clear that misregulation of stem cell fate and division is an important component of neoplasia (Gonzalez, 2007).

(Mechanotransduction and mechanical control of stem cell fate is reviewed by Sun et al. (32) and references therein).

In contrast, genes associated with bone mineralization, ossification, and regulation of stem cell fate were upregulated at 4 weeks.

Stem cell 'niches' are complex microenvironments with physical, chemical and biological cues, and have been implicated as directors of stem cell fate (Ohlstein et al, 2004).

Understanding how these circuits function in stem cell biology is important for enabling control of stem cell fate and cell reprogramming.