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This approach would essentially unravel the molecular basis of specificity at individual level that ultimately dictates the cellular physiology leading to the phenome variation.
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We highlight new positions for these proteins that suggest additional experiments to elucidate the basis of specificity.
Nitrilases have been classified into three major categories on the basis of substrate specificity, although some nitrilases exhibit broad substrate specificity.
On the basis of substrate specificity, they are classified as serine/threonine, tyrosine, dual specificity, or histidine protein phosphatases.
We are gaining an understanding of the molecular basis of resistance specificity and of the natural processes that generate different specificities.
Although fertilization is strictly species-specific, very little is known about the molecular basis of such specificity.
Overall, the ERAP1 homology model seems to provide an appropriate framework for at least a gross understanding of the basis of substrate specificity of ERAP1.
β-Glucosidases may be classified into three groups on the basis of substrate specificity.
The current study sheds light on the structural basis of substrate specificity of type-II FPPS of the spruce budworm.
The genetic basis of host specificity for animal and plant pathogenic bacteria remains poorly understood.
Thus, our results support a "repertoire for repertoire" hypothesis as the molecular basis of host specificity of plant pathogenic bacteria.
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