Sentence examples for basis of sequence similarities from inspiring English sources
These domains were clustered on the basis of sequence similarities into 33,879 domain families containing at least two members with less than 40% sequence identity.
On the basis of sequence similarities and mapping of the conserved residues to the crystal structure of NgoMIV we suggest that residues D160, K182, R186, R188 and E195 contribute to the catalytic/DNA binding site of the Ecl18kI restriction endonuclease.
These ESTs were categorized into different clusters on the basis of sequence similarities.
On the basis of sequence similarities, other twelve, previously uncharacterised, fungal TbDHN1 homologs were identified (Table 1).
This database consists of protein domain families, which are automatically classified on the basis of sequence similarities, where composition and size of the PFAM families vary significantly (34).
This database consists of protein domain families which are automatically classified on the basis of sequence similarities, built around Hidden Markov Models (HMM).
On the basis of sequence similarity, a similar mechanism would be predicted to occur in syndecan-4.
Filtering steps that included abundance filtration by selecting transcripts with FPKM ≥ 1 and grouping similar transcripts on the basis of sequence similarity (clustering) discarded on an average 46%% transcripts for each of the three fox samples (Additional file 2: Table S2).
However, the rationale to develop drugs to target the T. brucei kinome poses a conundrum: if mammalian and parasite protein kinases are sufficiently similar to be identified and classified on the basis of sequence similarity and are inhibited by typical inhibitors, will parasite kinase inhibitors lack host parasite specificity?
The fungal reference sequences were assigned to ecological functional groups (saprophytes, pathogens, ectomycorrhizae, arbuscular mycorrhizae) on the basis of sequence similarity using the default parameters of the GAST algorithm59 against the functional reference dataset60.
