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We then used a fluorescence resonance energy transfer (FRET) based G protein sensor similar to a previous sensor [14] containing different γ subunits to identify the mechanistic basis of response differences.
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If this is the case, explaining task specialization and the origins of division of labor on the basis of differences in response thresholds is difficult.
Naturally occurring variability to acute ozone in plants provides a valuable resource for examining molecular basis of the differences in responses to ozone.
Pharmacogenomics is the study of the inherited basis of interindividual differences in drug response.
Second, we examined the mechanistic basis of the differences in breast tumour cell responses to TSA, depending on tumour aggressiveness, and considered the transcriptional regulation of CXCR4 and Met, two genes important for tumour cell invasiveness (Benvenuti and Comoglio, 2007; Furlan et al, 2008).
Species-specific responses and dataset size were the basis of observed differences between GLM for the two species.
It is widely accepted that polymorphisms in the human genome are expected to play a key role in defining the etiologic basis of phenotypic differences amongst individuals in the aspect of drug responses and common disease predisposition [ 24].
However, because MC4100Z1 and Top10 are so closely related, it is likely that the genetic basis of this difference in circuit response to the host can be mapped, and the mechanistic causes determined.
The molecular basis of this difference in biological responses between MM and non-MM cell lines is not known but is currently being addressed by ongoing research.
However, this approach did not appear to improve the possibility to identify cancer-susceptible subjects on the basis of the response to radiation exposure; the differences between cases and controls was not significantly increased in family positive and BRCA positive as compared with family negative and BRCA negative.
"It opens up a window to the understanding of the genetic basis of individual differences in sleep duration.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com