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The CPRD is much larger than the UK biobank and would be particularly valuable to improve our understanding of the genetic basis of rarer phenotypes, if these could be linked to biological samples.
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Understanding the genetic basis of complex phenotypes in rice is a major challenge.
Progress in the field of strain engineering is being made by identifying the genetic basis of complex phenotypes, engineering new phenotypes, and combining beneficial phenotypes in industrial hosts.
Criteria for defining asthma endotypes on the basis of their phenotypes and putative pathophysiology are suggested.
This group of genes was originally defined in the 1970s on the basis of mutant phenotypes.
It can be used to establish a genetic basis of valuable phenotypes of rose flowers.
Genetic polymorphisms are the basis of diverse human phenotypes, disease susceptibility, prognosis and responsiveness to treatment.
In no case were insertions selected on the basis of phenotypes or lack thereof.
Understanding the genetic basis of phenotypes generally requires genotyping thousands of gene-targeted loci, genome-wide.
To clarify the cellular basis of the phenotype of Nanog-deficient blastocysts, we examined diapause blastocysts.
Discovering the genetic basis of a Mendelian phenotype establishes a causal link between genotype and phenotype, making possible carrier and population screening and direct diagnosis.
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