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For assessment of risk of bias, we evaluated studies on the basis of random sequence generation (selection bias), allocation concealment (selection bias), blinding (performance bias and detection bias) and incomplete outcome data (attrition bias).
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Berger [ 13] has added to the debate by presenting the logical consideration that successful control for bias cannot be assured on a basis of inclusion of adequate methods, (adequate generation of random sequence, allocation concealment, blinding/masking) alone.
The efficiency of random sequencing would increase to 18%-19 18%-19per gene basis if non-coding sequences were targeted [ 16].
At least some non-random sequences satisfy many of the measure one properties required of random sequences.
The outcomes in random sequences are thus patternless, or disorderly, in a way that is intuitively characteristic of random sequences.
On the basis of the random sequences included in Fig. 2, the present approach appeared to work for sequences longer than about 10 kb.
Dark figures are calculated on the basis of random sample surveys such as the British crime survey.
*Effect estimate and 95% CI estimated on basis of random effects model.
Summary relative risks were estimated on the basis of random effects models.
The children were allocated to treatment on the basis of a computer generated random sequence.
where Var denotes the variance of the random sequence.
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