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The in situ abundances of lignocellulolytic populations were determined on the basis of previously reported pyrotag libraries from the same field samples [31, 32].
The evaluation of a series of piperazinyl carbamates and ureas, designed on the basis of previously reported TRPV1 antagonists and FAAH inhibitors, led to the identification of some 'dual-action' compounds targeting both FAAH and TRPV1 or TRPA1 receptors.
The ZnCdSe/ZnS core-shell QDs and Au NPs were synthesized on the basis of previously reported methods [38, 39].
Because our results differ somewhat from those expected on the basis of previously reported studies assessing LDH mRNA expression by in situ hybridization, where LDH-H mRNA was predominant in cortex [41], it may be that regional LDH expression in the brain is regulated post-transcriptionally.
On the basis of previously reported results, an Arrhenius temperature dependence was selected.
In addition, four moth mitogenomes were selected as outgroups on the basis of previously reported relationships [ 66].
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On the basis of the previously reported effect size of genetic loci for DR (~1.40) [ 10], our samples had > 90% power to detect an effect SNP with MAF of 0.3 and > 80% power to detect an effect SNP with MAF of 0.2 at a level of significance of 0.05.
We carefully selected the drug levels for our in vitro (0 50 μg ml−1) and xenograft experiments (25 mg kg−1 per day), on the basis of the previously reported pre-clinical and clinical pharmacokinetic data of TMZ.
On the basis of the previously reported work on duplexes and triplexes, the linear slopes of the graph of eq 8 give the number of water molecules associated with each iM at the temperature studied, which, in our case, was physiologically relevant 37 °C.
In particular, the reported anticancer and chemopreventive natural product 7-isopentenyloxycoumarin was linked to different terminal amines, selected on the basis of our previously reported results.
On the basis of our previously reported benzopyran non-azole CYP51 inhibitor, scaffold hopping was used to design structurally diverse new compounds and expand the structure activity relationships of the lead structure.
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