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We assumed a prevalence of pre-eclampsia in the placebo group of 30% (on the basis of pilot data from our institution).
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Although some DCEs have been undertaken without undertaking a pilot exercise first, the benefits of initial piloting and analysis of pilot data econometrically are considerable.
Decision C: non-acceptance of pilot data: when a first pilot identifies the need for a substantial change that the pilot did not assess, even implicitly.
On the basis of our pilot data (3.2% of the age group being suitable and consenting) and assuming an average practice list of 4500 with 18% of people aged 50 69 (Office for National Statistics, 2004), 23 100 people from 29 practices were estimated to be required to identify 700 eligible participants consenting to colonoscopy and MMP9 determination.
On the basis of our pilot data and conservatively assuming a community prevalence of neoplasia of 6% (Thiis-Evensen et al, 1999; Lieberman et al, 2000), a sample of 700 people would be sufficient to estimate specificity within 4%95%5% confidence).
This maximum was established on the basis of preliminary pilot data, as has been noted, but also some consideration of memory constraints for the temporal order identification tasks.
On the basis of these pilot data, we increased the long duration condition to 1000 ms. The experiment was conducted onsite at various metropolitan Sydney BreastScreen and radiology practice locations.
On the basis of our pilot data, a previously overlooked intraoral anatomic location, the buccal mucosa, may prove to be of higher diagnostic value than others previously reported in terms of obtaining a diagnosis of amyloidosis.
On the basis of the pilot data, 10 pleasant and 10 neutral sentences were selected for use in the experiment (Table 1).
As many as 21 (81%) of pilot studies suggested the need for further investigation of the tested drug or procedure and did not report conclusive results on the basis of their pilot data.
On the basis of pilot study data, standard glass sizes were defined as 200 mL for beer, 105 mL for wine, and 45 mL for liquor, corresponding to 8g, 10g, and 13g of ethanol, respectively [ 26].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com