Sentence examples for basis of multiple sequence from inspiring English sources
Based on this, a sketch map of the 3D-motif C in mVAChT (mouse VAChT) could be postulated on the basis of multiple sequence alignment and homology modelling (Fig. 5D).
On the basis of multiple sequence alignment and homology modeling, invariable structural elements were defined, corresponding to the active site, the substrate binding site, the accessory binding sites, the Ca2+ and Cl− binding sites, a protease-like catalytic triad and disulfide bonds.
Secondary structure prediction was performed with SOPMA (http://npsa-pbil.ibcp.fr/cgi-bin/npsa_automat.pl?page=npsa_sopma.html) on the basis of multiple sequence alignments [76].
Of the 37 isolates, 33 were classified as genotype 3 on the basis of multiple sequence alignments of ctxB (10 ).
Since canine DNA sequence information on tenascinC, YKL39 and YKL40 was not available from public databases, degenerated primers were designed on the basis of multiple sequence alignment.
While ConSurf calculates conservation scores on the basis of multiple sequence alignment typically of hundreds of homologous protein sequences, ProBiS usually uses tens of locally similar structures.
To overcome this problem we used multiple structure alignments, when available, as a basis for multiple sequence alignments.
A bootstrapped NJ-tree was generated on basis of a multiple sequence alignment of all LacI-family TF homologs of L. plantarum, together with orthologous sequences for which experimental confirmation about the nature of the inducer could be retrieved.
A phylogenetic tree was constructed on the basis of a multiple sequence alignment of 112 sequences (the 74 PEDV sequences generated from this study and the 38 PEDV sequences available from GenBank).
On the basis of the multiple sequence alignment, we estimated the rate of evolution for each CP sequence in order to infer the selective constraints.
