Thus, the maternity of the nestling could not be resolved and the true genetic mothers were unlikely to have been sampled as all candidate females were excluded at least on basis of mismatches in two loci.
On the basis of mismatch-repair (MMR) functional status, CRCs can be subdivided into MMR-deficient, microsatellite unstable (MSI-H) and MMR-proficient, microsatellite stable (MSS) tumours.
Methods for indirect SNP discovery detect heteroduplexes on the basis of mismatch-induced altered DNA characteristics [ 4- 8], whereas typical direct SNP discovery strategies [ 9, 10] involve sequencing of locus-specific amplification (LSA) products from multiple individuals.
Many non-RE XL elements are also explored on the basis of size mismatch between Mg and XL, including Tl, Sb, Pb, Na, Te, Bi, Pa, Ca, Th, K, Sr an additional 55 ternary systems.
Although the basis of the mismatch between these data and our findings is unclear, both studies suggest a lack of linear correlation between lesion size and alteration of C6-aldehyde levels.
Therefore the basis of this mismatch between the two data sets may be due to differential responses of plants to exogenous application versus the in vivo generated C6-aldehydes.
For an example, faulty genes were detected on the basis of the mismatch between the normal gene sequences and the ones predicted by Boolean models in studying oxidative stress response [ 8].
Another point to note is that Luciano et al. did not correct for IQ, and given that reading and IQ tend to be correlated, the phenotype they studied would be rather different from those in samples of dyslexics, who are usually identified on the basis of a mismatch between poor reading and average or high IQ.
This provides an estimate of a significant change to be used in the power calculations, and requires that experiments used for the comparison are performed on the basis of sex mismatch (either in silico or in vitro, depending on the microarray platform used).
