Sentence examples for basis of miRNA profiles from inspiring English sources

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Accordingly, we tried to develop a similar approach aiming to distinguish these PTCL subtypes on the basis of miRNA profiles.

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Most of these studies assessed plasma/serum levels of miRNAs that were selected on the basis of miRNA profiling data in cancer tissues themselves.

Further, we update the clinical trials on the basis of miRNA profiling using patient blood samples as well as addressing the potential of miRNAs as novel biomarkers and therapeutics for soft tissue sarcomas.

The inclusion of miRNA profiling in systems toxicology approaches increases the mechanistic understanding of the complex exposure responses.

A number of miRNA profiling studies have implicated miRNAs in the MDR phenotype.

Therefore, the differential expression of some miRNAs in primary malignant melanoma and metastasized melanoma cells in comparison to benign melanocytes opens new horizons in the understanding of the pathogenesis and prognosis of malignant melanoma on basis of miRNA expression profile (Lujambio et al. 2008; Satzger et al. 2009).

In addition the basis of exploiting cellular miRNA profiles for detargeting AAV expression from specific cells is described.

For example, tools like MAGIA [ 21], MMIA [ 22] and mirConnX [ 23] perform integrated network analysis on the basis of miRNA target predictions and correlation between miRNA and mRNA expression profiles.

To extend sequence-based, localized analyses of SNP effect on miRNA binding, we proceeded to dissect the genetic basis of miRNA expression variation; we mapped miRNA expression levels as quantitative traits to loci in the genome as miRNA eQTLs, demonstrating that miRNA expression is under significant genetic control.

Primers were designed on the basis of miRNA mature sequence.

Correlation of control miRNA profiles across beadchips.

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