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Although genetically modified mice are powerful tools to investigate the molecular basis of many human diseases, they are less suitable for many preclinical studies.
In order to understand the genetic basis of many human specific traits, it is often relevant to ask whether particular genes are differentially expressed between humans and their closest living relative, the chimpanzee [4].
Given the importance of RPL11 and RPL5 as components of the p53 signaling pathway (Chakraborty et al., 2011), 5S RNP biology is an underinvestigated area of research that is relevant for understanding the basis of many human ribosomopathies.
Genome-wide association studies (GWAS) have become an important strategy for investigating the genetic basis of many human diseases, including diabetes, breast cancer, pancreatic cancer, and hypertension, amongst others (http://www.genome.gov/GWAStudies).gov/GWAStudies
Elucidation of the genetic basis of many human cancers has been aided by identification of recurrent genomic DNA copy number aberrations (CNAs) affecting dosage of target genes involved in cancer pathogenesis.
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Mutation and selection are thought to shape the underlying genetic basis of many common human diseases.
We argue here that bioinformatics can play an important role in addressing the complexity of the underlying genetic basis of many common human diseases.
This "executive functioning" capacity forms the basis of many daily human activities, such as planning, reasoning and thinking, and is known to be impaired in patients with schizophrenia [ 4].
Cereals have also become the basis of many industrial processes not designed for products for human consumption.
Researchers have made dramatic advances in understanding the genetic basis of many common diseases since the sequencing of the human genome was completed in 2003.
On the basis of many neuroanatomical and neuropsychological studies, Posner divided the human attention system into three independent networks: the alerting, orienting, and executive control networks.
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