Sentence examples for basis of linkage from inspiring English sources

The impact of recombination on genetic diversity of bacterial populations was first defined in the milestone work of Smith et al. [8], who proposed the "clonal," "panmictic," and "epidemic" population structures on the basis of linkage disequilibrium (LD) between multiple marker loci.

Using the tagger program implemented in Haploview 4.0 [40], tag single nucleotide polymorphisms (SNPs) across DDAH1 and DDAH2 genes, including the promoter region, were selected on the basis of linkage disequilibrium patterns observed in the Caucasian (CEU) samples genotyped as part of the International HapMap Project [41].

There were 118 (27%) patients who were assigned to the BRCA1 group on the basis of linkage or mutational data.

Additionally, the association observed in the later studies may be explained on the basis of linkage disequilibrium that exists between the TNF genes and HLA [ 38].

On the basis of linkage disequilibrium pattern, three genetic markers from SLC11A1 and one from the nearby IL8RB locus were selected and examined for association with TB susceptibility.

A polygenic score analysis was conducted using a thinned (on the basis of linkage disequilibrium) panel of 113,774 SNPs from the PGC-schizophrenia meta-analysis.

CHRNA7 was also an attractive candidate for schizophrenia on the basis of previous linkage results [ 17].

Misclassification of one patient from the 'DYT14' family had led to incorrect locus assignment on the basis of erroneous linkage.

The future availability of the porcine reference sequence will likely help us to understand the basis of this linkage heterogeneity.

Further sequencing and analysis of the region will be required to elucidate the basis of this linkage finding.

On the basis of this linkage map, several residual heterozygous lines (RHLs) have been developed from the progeny of this mapping population for fine-mapping of several QTLs.