Sentence examples for basis of its structural from inspiring English sources
In the present work, on the basis of its structural and mechanistic properties, a series of substrate analogues, including potential suicide-pseudosubstrates was synthesized and their putative inhibitory effects were tested using E. coli aspartate transcarbamylase as a model.
From the macroscopic perspective, phases can be identified utilizing a series of thermodynamic properties based on classical thermodynamics; from the microscopic perspective, a phase needs to be defined on the basis of its structural symmetry and the types of order found in the phase.
The RTPA models for system behaviors can be implemented in any programming language in order to realize the expected functions and behaviors of the system on the basis of its structural models.
PCNA interactors like Polδ, FEN-1, and Cdc9 could compete quite effectively with Elg1-RLC for PCNA interaction, since Elg1-RLC probably interacts with all three subunits of PCNA, on the basis of its structural resemblance to RFC.
Currently, CagA is classified into several groups, including Western CagA, East Asian CagA, African CagA and Amerindian CagA, on the basis of its structural diversity in the EPIYA-repeat region.
On the basis of its structural resemblance to tyrosine and Lineweaver Burk analysis showing competition with peptide substrate but not ATP, erbstatin was initially reported as a substrate phosphorylation site inhibitor.
in silico mining of microsatellites repeats may provide a useful basis for carrying out further investigation of its structural and functional characteristics.
This is the first time that an inhibitor is reported to have a better potency for EDN than for RNase A. The crystal structure of EDN 11c complex reveals the structural basis of its potency and selectivity providing important guidelines for future structure-based inhibitor design efforts.
To elucidate the structural basis of its reduced potency, we determined the ligand structure in complex with GPb at 1.8 Å resolution.
Therefore it is ideally suited to reveal the structural basis of its high-affinity interaction with FimH.
Characterization of the polymer chain and understanding of the structural basis of its properties is essential in optimizing and controlling the manufacture of reproducible drug substance.
