Sentence examples for basis of its efficacy from inspiring English sources

The ability to choose an agent on the basis of its efficacy and safety profile, and to match it to a patient and an indication, is a marked advance in our ability to address an important unmet need and prevent mortality and serious morbidity in patients at risk for thromboembolic disease.

While its structure and the basis of its efficacy are well understood, the genetic variability of HA coupled with current methods of vaccine production make it exceedingly difficult to simultaneously meet seasonal and pandemic needs on a global basis.

Thus, the synergy between the elements of this combination at low concentration could constitute the basis of its efficacy conferring a more appropriate therapeutic window.

On the basis of its efficacy, safety profile, and rare side effects, this drug may be an alternative therapy for management of insulin resistance in sepsis.

The efficacy of TMP-SMX as a form of PEP is likely closer to 82% on the basis of its efficacy as a prophylaxis for several infections such as toxoplasmosis and Pneumocystis carinii pneumonia (25 ).

For instance, the green tea component epigallocatechin-3-gallate epigallocatechin-3-gallate epigallocatechin-3-gallate apoptosis in sEGCGal cancers types, resulting in tumor growhichnhinhibits settinGDHhasbeenshown toe expromoteon of its efficapoptosisase in clinical trialseveral 218].

28 Finally, MM patients with associated AL amyloidosis can be considered for bortezomib-based therapy on the basis of preliminary evidence of its efficacy in this setting.

On the molecular basis of its clinical efficacy, FLX increases serotonin synaptic availability [ 5].

Although there is currently no universally accepted standard regimen for the first-line treatment of advanced NSCLC, cisplatin gemcitabine (CG) is widely used in Europe on the basis of its favourable efficacy and tolerability profile [ 1, 2].

These data suggest that activity of regorafenib against the tumor proliferation and survival pathway (RAS/RAF/MAPK) and tumor vasculature pathway represents the basis of its high clinical efficacy.

Lamivudine prophylaxis has been suggested on the basis of its well demonstrated efficacy; however, other nucleotides/nucleosides should be preferred for their lower propensity to provoke drug resistance, especially if immunosuppressive therapy is scheduled for more than 12 months.