Sentence examples for basis of its activity from inspiring English sources
Strikingly, an enzyme from Ideonella sakaiensis, termed PETase, was described to efficiently degrade PET at room temperature, but the molecular basis of its activity is not currently understood.
Surprisingly, though, BPA was found to be more potent in vivo than would have been expected on the basis of its activity in vitro.
Improving GE's properties, for example by increasing its uptake into a cell while not lowering its potency, requires the molecular basis of its activity to be thoroughly understood (Mariani et al., 2005).
DIAS1 (6) was selected for further evaluation (Fig. 2D) on the basis of its activity, relatively low molecular weight (258 Da), and predicted lower lipophilicity compared to HU-308 (c log P HU-308, 6.9; c log P DIAS1, 4.2).
If a stable interaction is the basis of its activity, then the antibody would be expected to act in a dose-dependent fashion at a comparable range of concentrations to α1-antitrypsin.
On the basis of its cytotoxic activity in vitro, xanafide was further evaluated for in vivo activity in two ER+ and ER− breast cancer cell lines, MCF-7 and MDA-MB-231, respectively.
On the basis of its superior activity and stability, the ultrafine PBSCF nanofiber has potential to be a very promising candidate of the next-generation electrocatalysts for OER.
To better understand the molecular basis of its biological activity, we used a multidisciplinary approach to generate an accurate model of the Hu 15C1 TLR4 complex.
The concentration of dental alveolar blood in extraction wounds after the oral administration of talampicillin (500 mg), cefaclor (500 mg), cefteram pivoxil (200 mg), cefuroxime axetil (250 mg), cefdinir (200 mg), and ofloxacin (100 mg) was determined in 338 patients and was assessed on the basis of its antimicrobial activity against Streptococcus isolated in odontogenic infections.
To this effect, we sought to investigate the molecular basis of its antimicrobial activity.
Even on the basis of its catalytic activity two mechanisms, not necessarily mutually exclusive, could be responsible.
