Sentence examples for basis of interim data from inspiring English sources

On the basis of interim data, an independent data monitoring committee advised halting study drug because of concerns regarding excess blasts and AML rates with romiplostim (interim hazard ratio, 2.51).

On the basis of interim data from a study in oocyte donors at risk of OHSS (Alvarez et al., 2007b), in which moderate/severe OHSS was reported for 24% (7/29) and 52% (13/25) in the dopamine agonist and placebo groups, respectively, 50 subjects per group were required for the present trial to show a significant difference between the highest dose of quinagolide and placebo.

An independent trial steering committee and an independent data monitoring and ethics committee provided oversight for the study; on the basis of three reviews of interim data there was no reason to stop or modify the trial on the basis of pragmatic stopping criteria.

The role of the DMEC is to consider the need for interim analyses of trial data, the implications of such analyses, and requests for release of interim data.

However, a recommendation for SSR made with knowledge of interim data introduces bias to the trial.

Finally, the study stopped enrolment after 398 patients on the basis of interim efficacy and futility analyses planned at 50%and75%5% of enrolment.

Projected accrual was 120 cases, but enrollment was stopped at 103 cases in July 2012 on the basis of interim analyses conducted after 5 years.

Interviews will be taken until data saturation is achieved on the basis of interim-analyses after each set of five to eight interviews, with a minimum of twenty interviews.

The trial was stopped for futility at the third interim analysis on the basis of complete data from 2,078 patients.

Each participating breast centre is assessed on the basis of these data and has to demonstrate improvements at the yearly interim audits and the three-yearly recertification audits.

Interim data from a registry of cluster headache patients continues to demonstrate the effectiveness of SPG stimulation therapy.