Sentence examples for basis of interaction specificity from inspiring English sources
Understanding the sequence and structural basis of interaction specificity in this family is important, as it may allow the prediction of new Bcl-2 family associations and/or the design of new classes of selective inhibitors to serve as reagents or therapeutics.
LRET assay with two different acceptors of the interaction specificity of individual TPR domains of human HOP.
The same principle forms the basis of our approach to studying interaction specificity.
This together with mutagenesis and deletion studies based on the comparisons will help to understand the basis of the specificity of the TF interactions.
There is continued debate over the molecular basis of stress specificity, which may be achieved through stress-specific interactions with components of a general defensome, posttranslational modifications, and/or the compartmentalization of stress proteins (Kültz 2005).
Such interactions could constitute the basis of substrate specificity in hOGA.
(C) Co-occurrence network showing interaction specificity of bacterial genera.
Nestedness refers to a structural property of the interaction network whereby species with higher interaction specificity tend to interact with the supergeneralists, with interactions that form proper subsets of those recorded for more generalized species.
Considering that diverse molecular tools are available for C. elegans, this nematode may in the future provide a valuable model system to dissect the molecular basis of specificity in invertebrate-pathogen interactions.
Previous studies have implicated the homeodomain as a major determinant of biological specificity within these proteins, but have not established the physical basis of this specificity.
