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The genetic basis of host specificity for animal and plant pathogenic bacteria remains poorly understood.
Thus, our results support a "repertoire for repertoire" hypothesis as the molecular basis of host specificity of plant pathogenic bacteria.
Understanding the genetic and molecular basis of host specificity in pathogenic bacteria is of great importance.
Understanding the genetic and molecular basis of host specificity in pathogenic bacteria is important for understanding pathogenic mechanisms, developing better animal models and designing new strategies and therapeutics for the control of microbial diseases.
We hypothesize that genes found to be polymorphic among M. avium subspecies isolated from different hosts will serve as ideal targets for future studies designed to elucidate the biological basis of host specificity and pathogenicity.
The genus Brucella, the etiological pathogen of brucellosis, is divided into at least ten species, including the six classical species: B. abortus (bovine), B. melitensis (caprine and ovine), B. ovis (ovine), B. canis (canine), B. suis (porcine), and B. neotomae on the basis of host specificity, antigenic differences and biochemical characteristics [ 1, 2].
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The recent publication of reference genomes and comparative genomics of the generalist M. anisopliae and the locust-specific pathogen M. acridum has further enhanced our understanding of the biology of these entomopathogenic fungi and the molecular basis of host-specificity [ 5, 13].
This functional genomic analysis provides the molecular basis for better characterizing the evolution of host specificity and virulence in pathogenic fungi.
These findings provide a strong foundation for investigations of the molecular basis of pathogenesis of SA-associated bovine mastitis, as well as a rational foundation for continuing the investigation of host specificity in this important human and animal pathogen.
Entry into the host system is a potential determinant of host specificity [5].
Knowledge of the degree of host specificity is important to the understanding of pathogen transmission dynamics.
More suggestions(19)
basis of stress specificity
basis of host specialization
basis of host tropism
basis of host cell
basis of sensitivity specificity
basis of resistance specificity
basis of host range
basis of host susceptibility
basis of interaction specificity
basis of host disease
basis of host adaptation
basis of host preference
basis of host choice
basis of stress specificity
basis of host affiliation
basis of sequence specificity
basis of ligand specificity
basis of strain specificity
basis of host resistance
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