Functional profiling methods exploit different definitions of modules in an attempt of understanding the functional basis of high-throughput experimental results [7].
So, this should not exclude possibility of differences between patient groups in terms of bacteria taxa or species that now call for further investigation on the basis of high-throughput sequencing results for cancerous and control microbiota.
Similar strategies might form the basis of high-throughput screening systems to identify engineered strains that are able to biosynthesize the molecule of interest.
In an attempt to understand the functional basis of high-throughput experimental results different functional profiling methods have been proposed [ 1].
Upcoming releases of AGD will contain information about gene function from large-scale deletion studies in A. gossypii and predicted protein-protein interaction data on the basis of high-throughput studies in S. cerevisiae [ 12, 13].
It has been estimated on the basis of high-throughput sequencing of mRNA that there are about 100 000 significant alternative splicing events in humans, derived from about 90% of the multiexon genes; this corresponds to an average of seven events per multiexon gene (Pan et al, 2008; Wang et al, 2008).
The seed networks presented here can be the basis for queries of high throughput datasets to identify larger, more comprehensive networks that participate in cellular fate specification and differentiation in the developing mouse retina.
The elucidation of the human genome and the development of high throughput gene sequencing technologies have led to the rapid understanding of the genetic basis of many inherited diseases.
They are treading cautiously, given the failure of "high throughput screening" in the early 2000s to improve efficiency by using robots to test millions of compounds.
Selection was on the basis of very high throughput and excellent tool matching capabilities.
These types of tests may form the basis for high-throughput screening assays employed in large-scale drug discovery or combinatorial chemistry efforts designed to identify new agents with specific molecular properties.
