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Our initial set of 34 biopsies (Supplemental Data 1, 'initial set') had been classified on the basis of germ cell types that are present in the seminiferous tubules.
Steel and W are genetic loci identified in strains of mice that exhibit sterility on the basis of germ cell deficiency.
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In this study, we sought to identify clusters of methylation associated SNPs as a basis for prediction of methylation landscapes of germ cell genomes.
As a further step toward understanding the molecular basis of the spermatogenesis defects illustrated in Fig. 2A and B, we analyzed the expression of a number of germ cell markers by qRT-PCR.
The germ plasm is a specialized region of oocyte cytoplasm that contains determinants of germ cell fate.
Disintegration of germ cell arrangement in seminiferous tubules and washing out of germ cells from the tubules were noted with the 10 mg dose.
A zebra fish model of germ cell aneuploidy.
Pathologically, these tumours include a wide variety of germ cell origins, making the tumour pluripotent [2].
The two main types of germ cell tumours are seminomas (40percentt) and non-seminomatous germ cell tumours (60percentt).
The two main types of germ cell tumors are seminomas (40percentt) and non-seminomatous germ cell tumors (60percentt).
Two modes of germ cell specification are recognized among vertebrates - predetermined (germ plasm) and inductive (regulative).
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