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Within the family, subgroups may be identified on the basis of functional differences, which appear to function as anion exchangers and anion channels (SLC26A7 and SLC26A9).
Nevertheless, even this coarse-grained information can be very helpful in understanding the genetic basis of functional differences between strains of the same bacterial species.
Distinct origins of the synovial fibroblast populations may be the basis of functional differences and would strengthen the notion that the FLSs of the lining and the fibroblasts of the sublining are distinct cell types.
Interestingly, the mutant protein showed lower α-helical content than the parent wt protein as well as Snl1-S suggesting, that increased flexibility of Snl1-S structure could be the basis of functional differences between Snl1-S and Snl1-M.
This study provides a first step toward understanding the molecular basis of functional differences between Symbiodinium clades by highlighting a number of genes with signatures consistent with positive selection along the thermally tolerant clade D lineage.
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This clustering was based on the gene expression variations among RI lines, the basis of which might arise because of functional differences between alleles arising from sequence variations, genetic background, or both.
Hence, it is difficult to reliably predict the properties of C2 domains based on sequence analyses alone, and the basis for functional differences among synaptotagmins is poorly understood.
These residues are potentially the most critical in defining the structural basis for functional differences between hMC4R and hMC1R.
To investigate the structural basis of these functional differences, we created and validated comparative three-dimensional (3-D) models of eEF1A1 and eEF1A2 on the basis of the crystal structure of homologous eEF1A from yeast.
It is thought that functional diversity within Symbiodinium may allow some corals to rapidly adapt to different environments by changing the type of Symbiodinium with which they partner; however, very little is known about the molecular basis of the functional differences among symbiont groups.
Kriegeskorte et al. [66] warn that selection of voxels on the basis of functional activation differences can lead to circular analysis and bias because if the selection process is based on the design matrix it creates dependencies between the experimental design and noise in the selected data which violates the assumption of random sampling.
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basis of functional diagnostics
basis of morphological differences
basis of functional classes
basis of functional data
basis of factual differences
basis of interindividual differences
basis of predefined differences
basis of functional insights
basis of functional hypotheses
basis of substrate differences
basis of functional categories
basis of specific differences
basis of functional residues
basis of functional compounds
basis of observed differences
basis of individual differences
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