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Clustering on the basis of expression data alone, however, only indicates co-expression, and does not directly identify co-regulation.
Integrated network inference aimes at determining interrelations between miRNAs and mRNAs on the basis of expression data as well as miRNA target predictions.
The other two contexts are for the unfused genes, one clustering solely on the basis of expression data and the other using the transcription factor binding dataset.
Results: The representation of a sufficiently large portion of genome enables computation of an upper bound on how much confidence one may place in influences between genes on the basis of expression data.
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These tumours were selected on the basis of the availability of expression data concerning the 47-gene set.
The proposed model-selection algorithm was used to annotate the likeliest regulatory interactions in E. coli on the basis of two independent sets of expression data, each containing many microarray experiments under a variety of conditions.
The integration of expression data from high-traffic genes may provide the basis for potentially accurate prognostic systems.
A reverse engineering strategy is presented, which is able to infer regulatory networks on the basis of gene expression data, making use of relevant selection criteria such as sparseness and robustness.
On the basis of gene expression data, the further aim of our study is to examine the effects of bolus T2 administration on the immobilization behaviour in the tail suspension test in C57BL6J and CD1 mice.
We also analysed genelists using gene-set enrichment analysis (GSEA) to identify statistically over-represented groups of genes on the basis of the expression data (Subramanian et al, 2005).
As shown in Figure 2 we observed diagnosis-specific clustering of keratinocyte cell lines on the basis of gene expression data.
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