Sentence examples for basis of efficacy from inspiring English sources

For new interventions, however, effectiveness data is usually not available and decisions are often made on the basis of efficacy data, with the uncertainty inherent in innovation [ 67].

20 The decision was made on the basis of efficacy and safety data from the Phase III TRANSFORMS and FREEDOMS trials.

Therefore, on the basis of efficacy and safety profile [ 17- 19, 23, 31], flavocoxid represents a novel antiinflammatory therapy and a potential approach for future clinical trials in patients with sepsis.

On the basis of efficacy and safety profile, diacerhein represents a novel antiinflammatory therapy for management of insulin resistance in sepsis and a potential approach for future clinical trials.

These doses were associated with reduced mortality rates, infection rates and shorter length of hospital stay for ICU patients, and they form the basis of efficacy data used for the current model.

However, safety information is based on short follow-up periods and on RCTs sized on the basis of efficacy outcomes, which do not properly assess safety in the long term.

Treatment guidelines typically categorize preventive migraine drugs according to the amount of evidence supporting their efficacy and the frequency and severity of side effects (see Table 4), rather than on the basis of relative efficacy.

The efficacy of TMP-SMX as a form of PEP is likely closer to 82% on the basis of its efficacy as a prophylaxis for several infections such as toxoplasmosis and Pneumocystis carinii pneumonia (25 ).

The need for neutralization validation as a basis of antimicrobial efficacy evaluations was emphasized by the fact that in studies without neutralizing agents in the sampling fluid, the efficacy of CHG was remarkably higher than in studies with neutralization [ 9, 10].

We suggest that increased level of transmissions of serotonin may be underlying reason basis of high efficacy of quetiapine in resistant and chronic forms of migraine (with and without aura).

The objective of this study was to develop a stable transfected cell line DLD-1 colon adenocarcinoma and at the same time characterize two different techniques of transfection on the basis of their efficacy.