Convergent evolution of LMs is at the basis of discovery algorithms like SLiMFinder [19] and DILIMOT [20], which search for over represented motifs in unrelated proteins with a common functional attribute.
Also, nine SNPs, already selected for replication for the OCPD and WF phenotypes on the basis of discovery dataset results (variables not phenotyped in the FinnTwin16) were included in the list of SNPs for de novo replication.
In total, 95,062 marker loci (SNPs, indels, and haploSNPs) were included on the array, of which 85,663 were developed on the basis of discovery in an octoploid germplasm discovery panel, 3,751 were discovered in the important diploid mapping parent F. iinumae F1D, and 5,648 were developed via a speculative, non-discovery based approach.
That these abstractions then formed the basis of profound discoveries about how the world actually works is one of the fundamentally weird things about science.
On the basis of these discoveries he rose to national prominence and was appointed as the Founding Director of Nephrology at the University of Alabama in Birmingham School of Medicine (UAB).
On the basis of these discoveries, scholars in the mid-20th century mistakenly thought that Mayan society was composed of a priestly class of peaceful stargazers and calendar keepers supported by a devout peasantry.
On the basis of new discoveries about the deep-ocean floor, Hess postulated that molten material from the Earth's mantle continuously wells up along the crests of the mid-ocean ridges that wind for nearly 80,000 km (50,000 miles) through all the world's oceans.
Recently, the National Cancer Institute announced $96 million in grants over 4 years to support post-GWAS cancer studies to replicate and understand the biological basis of gene discoveries [ 7].
The receptor tyrosine kinase c-MET has recently been implicated in resistance to EGFR-targeted therapies and, on the basis of these discoveries, therapies directed against c-MET are in development [ 64].
