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A two-step study on the basis of differential display and macroarray analysis of six oncocytic thyroid adenoma samples showed that 12 of the 30 genes upregulated at least two-fold in the tumours were mtDNA-encoded genes (Jacques et al, 2005).
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The results of differential display were confirmed by quantitative RT-PCRs performed on a large number of rat brains to exclude the possibility that the differentially displayed fragments found represent artifacts sometimes present in differential display applications (Liang and Pardee, 1995).
Therefore, both constitutive and induced patterns of differential gene expression can be studied following the technique of differential display.
This result also demonstrated an excellent reproducibility of differential display patterns recorded on a DNA sequencer.
Additionally, using a fluorescent assay that was reported to sort putative CSC from lung cancer, breast cancer, and multiple myeloma [26], [27], [28] on the basis of differential ALDH activity, a small fraction of the MPE-derived primary tumors displayed the ALDHhi/CD44+ phenotype (Figure 6).
More generally, we propose that the cell tropisms displayed by different strains of HIV-1 in culture can largely be explained on the basis of differential requirements for cell surface CD4 and/or coreceptor expression levels.
Neural precursors within these formations were isolated by selective enzymatic digestion and further purified on the basis of differential adhesion.
It distinguished (GT) n repeats on the basis of differential mobility of amplicons with different sizes.
On the basis of differential expression analysis, HsfC1 was the most stress-responsive of all Hsfs.
On the basis of differential methylation observed in patient samples, a penalized logistic regression was performed.
Consistent with the results of the differential display method, quantitative RT-PCR analysis showed that SAPAP1 in the NAc was regulated by the delayed action of PCP.
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