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Such a small difference is unlikely on the basis of current trial evidence of differences in lymphoedema and arm symptoms, including the NSABP-32 (5% difference in patient-reported moderate severe arm swelling at 36 months, Land et al, 2010) and the ALMANAC trial (7% difference in the proportion of patients reporting substantial arm swelling at 18 months, Fleissig et al, 2005).
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However, the need for dual antiplatelet treatment would be unlikely to be less than six months for biodegradable polymer stents on the basis of the current trial designs, in which the minimum requirement has been six months.
It is this trial that forms the basis of current treatment recommendations for this disease [ 4].
The hypothesis that inhaled NO administration will improve microcirculatory perfusion without significant impairment of systemic hemodynamics is supportable on the basis of current data, but will need to be tested in clinical trials.
Active treatment with docetaxel for 90 days was assumed (reflecting the median therapy duration in major randomized controlled Phase III trials 15– 17), the costs of which were assessed on the basis of current ex-factory prices.
But even on the basis of current expectations, the shares look cheap in comparison with peers.
These are the basis of many existing mesh generation programs and the basis of current research.
These patients formed the basis of current analysis.
An independent data monitoring committee (IDMC) will assess: 1. Safety, especially any unexpectedly high frequency of serious adverse events; 2. Data compared with previous experience which are the basis of the current the trial; 3. Any safety or efficacy data that do not justify the continuation of the trial as planned, including statistically significant differences between treatments.
On the basis of the current clinical trial and from the perspective of the Chinese healthcare system, the results of these studies are consistent with ours.
The results of the current trial support this postulation.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com