Sentence examples for basis of complex disorders from inspiring English sources

Nica, A.C. & Dermitzakis, E.T. Using gene expression to investigate the genetic basis of complex disorders.

In brief, we demonstrate an example of ICA analysis on SNP data yielding functionally meaningful clusters, which motivates further application of data-driven approaches as a complimentary tool for hypothesis-based methods to enrich our knowledge on the genetic basis of complex disorders.

The genetic basis of complex disorders are notoriously difficult to characterise, as the contributing factors can vary greatly between affected individuals and may be masked by undetermined environmental effects.

This has led to new insights into the genetic basis of complex disorders such as autism and other neuropsychiatric disorders, leading to further debates about the role of such variants in heritability calculations (Gratten et al. 2013).

Genome-wide association studies (GWASs) have helped to elucidate the genetic basis for a number of complex disorders.

Given a number of large-scale efforts to quantify genetic profiles and other markers for thousands of cancer patients and exponential increase in computing power, we believe that Geninter will be a useful tool to identify combinatorial survival effects of multiple attributes, which provide a solid basis for advanced analysis of complex disorders.

This general systems approach can thus identify candidate causal variants and the components of gene regulatory networks (GRN) to enable understanding of the mechanisms of complex disorders on a tissue- or cell-type basis.

Furthermore, most existing studies examining the genetic basis of PE have focused on single nucleotide polymorphisms (SNPs), which explain only a small proportion of the overall heritability of complex disorders.

Genetic Networks of Complex Disorders: from a Novel Search Engine for PubMed Article Database.

Hailiang's research focuses on the genetics of complex disorders, especially autoimmune and psychiatric disorders.

Temporomandibular disorders (TMD) comprises a heterogenous group of complex disorders having varied and often multifactorial aetiologies [1, 2].