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To understand the molecular basis of cold adaptation of proteins, we analyzed proteomes of psychrophilic and mesophilic bacterial species and compared the differences in amino acid composition and substitution patterns to investigate their likely association with growth temperatures.
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The psychrotrophic bacterium has since been used as a model system for understanding the molecular basis of cold-adaptation [3] [6], [33].
High altitudes demand a degree of cold adaptation plus adaptation for low air pressure and the consequent low oxygen.
High altitudes demand a degree of cold adaptation, as well as adaptation for low air pressure and the consequent low oxygen.
Thatje describes Antarctic organisms as "the champions of cold adaptation".
Our results provide new insight into the molecular mechanism of cold adaptation of food-spoilage LAB that cause food quality defects during cold storage.
On the other hand, Tr. bactrae aborted their emergence upon storage, indicating the lack of cold adaptation capability.
Whereas many theoretical and experimental studies have been devoted to clarify the molecular basis of the adaption of thermophilic enzymes to high temperatures, comparing single thermophilic proteins with their mesophilic counterparts and systematically examining different properties for families of proteins [ 10, 55, 56], molecular mechanisms of cold adaptation are still relatively unknown.
Many of the transcripts identified encode proteins of unknown function, indicating our lack of knowledge of cold adaptation in prokaryotes.
The transcriptome resource from this study will aid future investigations of cold adaptation and thermal response of polar ectothermic species.
Elucidating the low temperature transcriptome may highlight molecular mechanisms of cold adaptation in this Arctic bacterium [ 30].
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