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Age groups were defined on the basis of age at baseline.
Cases were matched 1 : 1 to controls on the basis of age at donation (±1year) and time in freezer (±1year).
Five of these were found to have died at the time of the study, and 91 were excluded on the basis of age at oophorectomy.
The multiple linear logistic regression analysis of the probability of breast cancer patients having a germline mutation in the BRCA1 or BRCA2 gene on the basis of age at diagnosis and family history of breast or ovarian cancers.
In addition, stratified analyses were carried out on the basis of age at baseline, history of prostate cancer, race, history of diabetes, current BMI, and BMI at age 18 years.
Clearly, further research on the genetic basis of age at onset would be of interest as the trait may serve as a proxy for both heavy use and experimentation with other drugs.
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To control as finely as possible for confounding by age, calendar time, and any possible two-way interactions between these two time scales, we stratified the analysis jointly on the basis of age in months at the start of follow-up and calendar year of the current questionnaire cycle.
The two treatment groups were well balanced on the basis of age, sex, and other characteristics at baseline (Supplementary Online Table 1), and no baseline characteristic was significantly different between the two groups (Hudes et al, 2007).
In studies that did not collect data on diabetes type, this information was defined on the basis of age of diagnosis, with a cutoff at age 30 years to use as many studies with detailed information other than types of diabetes.
We divided the participants into eight subgroups on the basis of age of smoking initiation, level of smoking at the baseline of the trial, and exercise during leisure time (Table 1).
When stratified on the basis of the age at menarche, i.e., < 12 years, 12-15 yeand and > 15 years, the incidences of AIA were 53.3%, 35.3% and 15.4%, respectively, and AIA manifested significantly more frequently as the age at menarche became lower (p = 0.036).
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