Sentence examples for basis for variant from inspiring English sources

Variation in cis-regulatory information content may therefore reveal the genomic basis for variant alleles with unique spatio-temporal properties.

In regions where no nucleotide or protein conservation data are available, VAAST 2.0 uses allele frequencies and global amino acid substation frequencies as the basis for variant prioritization; in regions where conservation information is available, VAAST 2.0 supplements this information with PhastCons scores Yang, 1995, which cover 99.9% of the human proteome.

We compare results using the RefSeq and Ensembl transcript sets as the basis for variant annotation with the software Annovar, and also compare the results from two annotation software packages, Annovar and VEP (Ensembl's Variant Effect Predictor), when using Ensembl transcripts.

Comparative analyses with BeadChip data and known variants causing coat color and disease phenotypes suggested that our sequencing data with a mean coverage of 11-25X provide a reliable basis for variant detection despite possible limitations due to lower sequence coverage in specific regions and errors in the reference genome that might simulate genetic variants [ 11].

Quantitative trait locus (QTL) mapping has successfully identified the genetic basis for many variant traits in sticklebacks [4].

Furthermore, the structural resolution of Bacillus stearothermophilus MutY has provided a structural basis for these variants [Fromme et al., 2004].

Understanding the functional basis for genetic variants associated with human complex traits is, therefore, critical for understanding the underlying biological processes.

The molecular basis for the 274Y variant in seasonal influenza A virus (H1N1) virus and the mechanism by which this resistant variant became the dominant population remain unknown.

The Tiger II served as the basis for one production variant, the Jagdtiger casemated tank destroyer, and a proposed Grille 17/21/30/42 self-propelled mount for heavy guns that never reached production.

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Anecdotal evidence, especially from journal editors, suggests that these issues are poorly understood by researchers who fail to mention the version number of reference sequences that they have used as the basis for reporting sequence variants.