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We used mixed block/event-related fMRI design to establish the neural basis for this effect.
There appears to be a physiological basis for this effect: Studies show that just fantasizing about a wish lowers blood pressure, while thinking of that same wish — and considering not getting it — raises blood pressure.
To explore a mechanistic basis for this effect, we turned to focal adhesion kinase (FAK), a central player in adhesion signaling previously implicated in angiogenesis, and its homologue, proline-rich tyrosine kinase 2 (Pyk2).
PBP4 has recently been shown to act as a sensor of the presence of penicillins in Pseudomonas aeruginosa, and our models offer a clue to the structural basis for this effect.
We studied the influence of spectral structure of the contextual stimulus on context dependent encoding of speech at the brainstem, in an attempt to understand the acoustic basis for this effect.
The basis for this effect, contact guidance, was discovered more than 50 years ago and has spurred scientific investigations of cell substratum interactions based on the geometric shape, width, and depth of features at a size scale similar to subcellular features.
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To investigate the neurobiological basis of this effect, we probed for differential activation patterns as a function of whether participants followed vs. ignored advice.
The basis for this cooperative effect of CGRP and glutamate is not clear.
One possible basis for this opposite effect could be the status of VGCCs in the two cell lines used.
The basis for this differential effect remains to be resolved but may be to due differences relating to their binding affinities to fodrin.
A major molecular basis for this suppressive effect is thought to be due to the decreased expression of motility- and invasion-related genes, but it is possible that it partly reflects the reduced cell viability.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com