Sentence examples for basis for the substrate from inspiring English sources
This structural feature forms the basis for the substrate specificity of DIS3L2 (Faehnle et al., 2014).
This study also provides the structural basis for the substrate specificity of cN-II, where Arg202, Asp206, and Phe157 seem to be important residues for purine/pyrimidine selectivity.
The structural basis for the substrate specificity of Ure2p enzymatic activity is an interesting problem that is fundamental to understanding the in vivo roles of Ure2p and its relationship to the GST structural family.
Our results define the molecular basis for the substrate specificity of a DEAD-box protein.
The structural basis for the substrate specificity and calcium activation has recently become apparent from the X-ray structure of the MCA2 from T. brucei.
Additionally, the structural effects of the positive mutations were investigated to analyze the structural basis for the enzyme substrate specificity with the target substrate.
The evolutionary basis for this substrate selectivity is discussed with respect to the homologous dienelactone hydrolase.
To investigate the peptide substrate specificity for Hsp40 Ydj1, we tried to synthesize different peptides designed on the basis of the substrate GWLYEIS (Table 2).
This provides the structural basis for understanding the substrate binding properties as well as conformational change upon substrate binding (Mulligan et al., 2014).
In this study we use x-ray crystallography, free-energy molecular dynamics (MD) simulations, and electrophysiology to uncover the atomic basis for the different substrate specificity of these highly similar channels.
We have sought the structural basis for the differing substrate specificities of human glutathione transferase P1-1 (class Pi) and human glutathione transferase A1-1 (clAlphalpha) by adding an extra helix (helix 9), found in the electrophilic substrate-binding site (H-site) of the human class Alpha enzyme, at the C terminus of the human class Pi enzyme.
