Sentence examples for basis for the specificity from inspiring English sources

Despite these biological studies, the structural basis for the specificity of substrate interactions of AUS remains elusive.

The first UCK structure provided the structural basis for the specificity, catalysis, and regulation of human uridine-cytidine kinase, which give clues for the design of novel antitumor and antiviral ribonucleoside analogs that inhibit RNA synthesis.

The crystal structure of this inhibitor (AR_F8) in complex with caspase-2 reveals the molecular basis for the specificity and, together with kinetic analyses, the allosteric mechanism of inhibition.

Thus, the molecular basis for the specificity of their differential interactions remains poorly understood.

The basis for the specificity of RI-evasive variants for cancerous versus noncancerous cells has been unclear.

The direct interaction of transcription factors (TFs) with DNA regulatory sequences forms the basis for the specificity of transcriptional regulation.

To interrogate the basis of the specificity of 4-MDDT for AKR1C3, we performed ligand-protein docking calculations using our published AKR1C3 structure (Lovering et al, 2004).

What is the basis for this specificity?

To provide a structural basis for enhancing the specificity of these benzoxaborole antifungals, we determined the structure at 2.2 Å resolution of the C. albicans editing domain in complex with a related compound, AN3018 (6- ethylamino -5-fluorobenzo[c][1,2]oxaborol-1 3H -ol), using AMP as a surrogate for the 3′ adenosine of tRNAleu.

This structural feature forms the basis for the substrate specificity of DIS3L2 (Faehnle et al., 2014).

This study also provides the structural basis for the substrate specificity of cN-II, where Arg202, Asp206, and Phe157 seem to be important residues for purine/pyrimidine selectivity.