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These studies provide a structural basis for the rational design of improved Ca2+-sensitive probes.
The spatial display of the four identical active sites represents an ideal basis for the rational design of bivalent inhibitors.
We also introduce the concept of depercolation as a basis for the rational optimization of tissue repair.
The results of this work provide a scientific basis for the rational strength design of backfill mine.
These findings provide a basis for the rational design of functional hybrids with precisely defined mechanical properties.
The model developed provides a solid basis for the rational design of optimised fermentation of cheese whey.
The results thus provide insights into the mechanism of action of this antifolate drug and constitute the basis for the rational design of more selective inhibitors of SHMT.
Dissection of the PRRSV host interaction is the key in understanding PRRSV pathogenesis and will provide a basis for the rational design of vaccines.
This compound was the basis for the rational design of a series of second-generation NT(8 13) analogues (KH1 KH30) studied in this paper.
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The layout created pleasant vistas, improved traffic patterns, and provided the basis for the future rational development of the city.
Together, these compounds and associated data form the basis for the future rational design of more potent substrate analogue OGT inhibitors.
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