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Higher durability of concrete compared to wood also provides an important basis for the preference of concrete as the construction material for railway track sleepers.
The basis for the preference to CRF in CRF2-R mice is not clear, but it may be a consequence of the rewarding effects of dopamine release caused by CRF activation of CRF1-R expressing neurons in the ventral tegmental area [5], [35].
The mechanistic basis for the preference of recruiting autoreactivity to neuronal antigens remains unclear.
Experiments were also designed to establish whether dsRBZFPs such as JAZ have differential binding activities for host dsRNAs compared to viral RNAs and to evaluate the structural basis for the preference of dsRBZFPs for binding to dsRNA over DNA and tRNA.
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With respect to scarce resources, the absence of an adequate financing basis for PGIR, the preference for short-term interventions in routine health care, as well as the stated lack of adequate concepts of intervention, the development and evaluation of shortened interventions could contribute to spreading the provision of PGIR in inpatient depression treatment in Germany.
Our structural data reveals the basis for this preference - in E. coli SSADH a three-residue deletion (of the human sequence 261RKN263, Figure S2) in the loop connecting s5C and h6 permits accommodation of the extra phosphate group of NADP+ (2'phosphate: Figure 3B, 4A and B).
Understanding the basis for this preference might shed light on how DNA replication and DNA repair depend on the nuclear lamina network [7], [85], [86].
"The physics basis for the human preference for rectangular frames that 'resemble' the golden ratio is easy to find on Google," Bejan tells me.
To investigate the basis for the subsite preference within Lgl, we examined a series of mutations in the context of Lgl ASA.
DOI: http://dx.doi.org/10.7554/eLife.04630.018 Collectively our results elucidate the basis for the physiological preference of the DEAD-box protein Mss116 for ATP and RNA, but also show that the helicase core has a surprising degree of substrate ambiguity.
The molecular basis for the differential preference has also been investigated and appeared to involve a 'resolving Cys' within the α2 helix of the Trx-dependent GPxs [ 5, 18, 19].
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