Sentence examples for basis for the involvement from inspiring English sources

Although FHIT protein expression is lost or reduced in many types of human cancers [9], the mechanistic basis for the involvement of intron 5 in genetic risk of prostate cancer is not apparent.

Given the overwhelming evidence that miRNAs are important regulators of tumorigenesis [3], [6], identification of miRNA targets is necessary in order to understand the mechanistic basis for the involvement of miRNAs in cancer.

Since BCR (BCR-ABL1) and Akt are cell signaling molecules critical for the proliferation of CML cells [22], our finding provides a molecular basis for the involvement of AQP5 in the progression of CML.

It has been previously suggested that transcription can promote the formation of DNA breaks along the sequence being transcribed [28], providing a possible basis for the involvement of Alus in the initiation of NHEJ.

Although robust evidence is available from various lesion studies showing that lesion to granule cells impaired motor learning [2], [49], [50], our study has for the first time demonstrated that change in NMDAR function in granule cells constitutes a molecular basis for the involvement of the cerebellum in GEI in facilitating the development of better motor skill learning.

Consistent with previous reports using other cell lines, we found that PRL-3 promotes the proliferation, migration and invasion of LoVo colon cancer cells, which provides a firm basis for the involvement of PRL-3 in tumour metastasis.

This simple but convincing experiment was the basis for suspecting the involvement of endogenous IGFBPs in the loss of IGF-1 effects in OA chondrocytes, and it was a prerequisite to justify their targeting.

Although how MRH2 coordinates AF and MT organization or dynamics remains to be determined, MT organization is the basis for MRH2 involvement in the MT and AF cross-talk during root hair tip growth.

The merged sustainability tool, based on the MDST and the BVT, should preferably be applied initially by experts as a basis for the communication and involvement of key stakeholders in the decision process.

Communication throughout the assessment process helps demystify the approach, provides the basis for increased involvement among relevant stakeholders, and is especially important once assessment results are collected and returned for stakeholder reflection and utilization [ 23].

The authors of the ACCP's White Paper on Herbal Products argue, for example, that "the basis for pharmacist involvement with herbal products is an extension of their established roles in pharmaceutical care, clinical pharmacy practices, and collaborative health care teams" (p. 883) [ 9].