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The interactive sequences identified in the homology models (Figs 4&5) are the basis for the interactions between tubulin and αB crystallin subunits in the regulation of tubulin assembly by αB crystallin.
To start addressing the molecular basis for the interactions between the flavivirus MTase and longer capped RNA substrates, we solved the X-ray crystal structure of DENV-3 MTase in complex with a 5'-capped octameric RNA at 2.9 Å resolution.
This orientation further forms the basis for the interactions of the heterodimers in the hexamer.
Finally, our study does not provide a mechanistic basis for the interactions observed.
Further investigations should also tackle the structural basis for the interactions of nTRAIL-R2 with proteins of the Microprocessor complex.
Now, writing in eLife, Tom Alber of the University of California at Berkeley and colleagues including Ursula Schulze-Gahmen as first author report a crystal structure that reveals the molecular basis for the interactions between P-TEFb and AFF4, helps to reveal how this complex is bound by the viral Tat protein, and suggests new strategies for therapeutic intervention (Schulze-Gahmen et al., 2013).
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Karlberg, T. et al. Structural basis for the interaction between tankyrase-2 and a potent Wnt-signaling inhibitor.
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Several theoretical models provide the basis for the interaction of the constructs of external social pressures during rapid attitude formation.
Although the interaction between PTP-Bas PDZ1 and TAPP1/2 is a therapeutic target for diabetes, the structural basis for the interaction has not been elucidated.
The structural basis for the interaction of novel inhibitors with tubulin was investigated by molecular modeling, and we have proposed binding models for these hit compounds with tubulin.
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basis for the dynamics
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