Sentence examples for basis for the defect from inspiring English sources
First, what is the mechanistic basis for the defect observed in Pol II CTD phosphorylation cycling and is this the direct cause of increased transcription observed in the RNF20 depleted cell line?
The molecular basis for the defects responsible for the developmental arrest of RAS within hepatocytes as well as the identity of the antigens involved in the protective immune response directed at the pre-erythrocytic stages remain unknown.
To better understand the mechanistic basis for the defects in osteoclast differentiation and survival, we investigated the role of TIEG1 in activation of pathways known to be involved in these processes.
The subtle differences that have been uncovered between Sar1A and Sar1B in these studies might also provide an explanation for the molecular basis of the defect in CMRD.
Although the basis for this defect is unknown, our study suggests that loss of self fertilization can be rescued by out-crossing, which might be an important means of generating increased diversity in the wild.
Both the experimental and the numerical results were in good agreement with predictions according to the R6 method and provided a basis for the engineering defect assessment of brazed components based on failure assessment diagrams.
To further clarify the basis for the platelet defect, we examined whether thrombocytopaenia in BCL-2tg mice is platelet-intrinsic or -extrinsic.
A lower rate of protein synthesis may be the underlying basis for the growth defect documented in kcs1Δ yeast strain [ 13, 15].
To begin to understand the basis for these defects in cellular DNA metabolism, we tested the ability of WRN in defined genetic backgrounds using yeast as a model system.
Without excluding the involvement of secondary histological alterations, the data presented in this work provide a cellular basis for the neuropsychiatric defects induced by prenatal inflammation.
To investigate the basis for the activity defects, we determined whether Q169 modulates hTERT stability, conformation, and physical interactions with hTR.
