Sentence examples for basis for the alterations from inspiring English sources

These observations provide new insight into the molecular basis for the alterations in neurite outgrowth and axonal viability associated with the CMT disease state.

Increased expression of Fas receptor and lower levels of sFas may provide the basis for these alterations that in turn may promote the rupture of tendons.

To examine the cellular basis for these alterations in bone, we examined the impact of combined Pkd1 and Kif3a deficiency on cell proliferation, osteoblastic differentiation, and gene expression profiles in cells isolated from calvaria of newborn wild-type, single heterozygous and compound heterozygous Pkd1 and Kif3a deficient mice (Fig. 3).

Inflammation is an underlying basis for the molecular alterations that link aging and age-related pathological processes.

We also observed that some ACRD cases have a low value for the 5α-THF/THF ratio, indicating enhanced 5β-reductase activity, or concomitant deficiency in 5α-reductase activity, though the basis for this alteration in activity is unknown.

The molecular basis for this alteration in RNA-binding properties is proposed to result from the inability of the RNA to induce a change in the structure of the free protein to produce a high-affinity complex.

Our data are consistent with these studies and provide a functional basis for the association of the alteration of the Trx/TrxR enzymatic system, the impairment of SNO homeostasis and tumor proliferation in an ER+/p53 intact setting.

Russia on Saturday blocked passage of a U.N. Security Council resolution that would have declared that Sunday's referendum "can have no validity, and cannot form the basis for any alteration of the status of Crimea". The veto was expected, but in a possible sign of Russian isolation, Moscow's close ally China opted to abstain rather than join Moscow in vetoing the measure.

It called on all countries to "desist and refrain from actions aimed at the partial or total disruption of the national unity and territorial integrity of Ukraine" and declared that the referendum "having no validity, cannot form the basis for any alteration of the status" of Crimea, a peninsula in southern Ukraine that Russian troops seized earlier this month.

Therefore, these changes are the basis for important alterations linked to aging [ 11- 15].

We next sought to address the cellular basis for the observed dendritic morphology alterations.