Sentence examples for basis for rational drug from inspiring English sources

Knowledge of its three-dimensional structure would provide a basis for rational drug design.

Our structures presented here can help deepen our understanding of this process and provide structural basis for rational drug design.

The two crystal forms revealed conformational flexibility in the binding site and extend the experimental basis for rational drug design.

The PKCι BIM1 complex is the first kinase domain crystal structure of any atypical PKC and constitutes the basis for rational drug design for selective PKCι inhibitors.

Because HuR is involved in many diseases (e.g., cancer, cachexia, and inflammatory bowel disease), the presented structure may provide a basis for rational drug design.

The model of the receptor-ligand complex produced forms a basis for rational drug design of agonists and antagonists for this G-protein-coupled receptor.

The structure determination of this peptide agonist is important in understanding the molecular basis of peptide ligand recognition by the receptor and for rational drug design.

Here we review the structural basis of ligand binding to secretin family GPCRs, concentrating on recent progress made on the structural basis of RAMP-modified GPCR pharmacology and its implications for rational drug design.

Prospects for rational drug design are highlighted.

For instance, molecular dynamics has been utilised for rational drug design for the influenza neuraminidase [ 7].

The approach presented therefore provides a valuable tool for rational drug development.