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Comparative genomics can be an initial step in finding the genetic basis for phenotypic differences among bacterial strains and species.
Genetic variation exists between individuals (or strains) of all organisms and it makes up the genetic basis for phenotypic differences between individuals.
They also allow researchers to unravel genetic basis for phenotypic differences between japonica and indica, such as the protein and amylose equivalence of seeds, the grain yield and nitrogen utilization [ 7, 8].
If common-garden or reciprocal transplant studies show a genetic basis for phenotypic differences in space, then it might seem reasonable to infer the same for the variation in time.
Further inbreeding and crossbreeding of these and other genotypes can be used to dissect the genetic basis for phenotypic differences, yield useful markers, identify linked genes, and ultimately contribute to mapping and assembling the A. fimbriata genome sequence.
The precise genetic basis for phenotypic differences between species is seldom known, but there is no doubt that species are different because their genomes are different, which is to say they have different DNA sequences.
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The comprehensive identification of polymorphisms among individuals within a species is essential for studying the genetic basis of phenotypic differences and for elucidating the evolutionary history of the species.
Finally, we correlated proportion of hybrid ancestry with phenotypic traits for a subset of individuals in the contact zone, as a way to control for the influence of environment and therefore test for a genetic basis of phenotypic differences between the coastal and interior lineages.
Genome Biology 4(11): R72. for phenotypic differences between humans and for susceptibility to genetic disease.
Building on my doctoral work, I am also interested in how differences in this circuitry may account for phenotypic differences seen across development and between species.
In contrast, with the much richer information from whole-genome sequencing, it should be possible to directly discover many of the variants causal for phenotypic differences.
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