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Subsequent studies established that olaparib, a potent PARP inhibitor, yielded notable clinical activity in BRCA mutation carriers with breast and ovarian cancers (Fong et al, 2009), providing the basis for ongoing trials (Moore et al, 2014).
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We also searched trial registries for ongoing trials.
We also searched trials registers for ongoing trials.
Finally, we searched for ongoing trials on https://clinicaltrials.gov/.gov/
Both reviewers also independently searched the websites for ongoing trials.
Current controlled trials http://www.controlled-trials.com and clinicaltrials.gov were also checked for ongoing trials.
In addition, we manually searched a website of clinical trials for ongoing trials.
We also searched Current Controlled Trials and ClinicalTrials.gov for ongoing trials.
We also searched the WHO clinical trial registry platform and the metaRegister of Controlled Trials (mRCT) for ongoing trials.
As both RNase 1 and Globo H are the basis for ongoing clinical trials, our discovery links two molecules that are now in the clinic.
Animal studies indicated that vasopressin regulates cystogenesis [ 33], which has been basis for ongoing clinical trials regarding the effect of vasopressin antagonists on cyst growth and deterioration of renal function in patients with PKD [ 34].
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