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Hence, it is difficult to reliably predict the properties of C2 domains based on sequence analyses alone, and the basis for functional differences among synaptotagmins is poorly understood.
These residues are potentially the most critical in defining the structural basis for functional differences between hMC4R and hMC1R.
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The molecular basis for the functional differences between meningococcal PilC1 and PilC2 variants could be associated with sequences specificities in the aminoterminal part of the protein [34].
The basis for the functional difference between the effects of E-cadherin and cadherin-11 is not clear.
Importantly, we mapped and ordered six LMW-GS genes within the Glu-D3 locus (compared to only one at the Glu-D3 of the 1D composite map, see above), which provides a useful basis for investigating potential functional differences among the different Glu-D3 LMW-GS genes in the future.
Several studies have for instance suggested that dimerization may influence the GTPase and kinase functions39, indicating that different dimer conformations may lie at the basis of these functional differences.
However, no information is provided on the molecular basis underlying these functional differences.
Obtained data were basis for functional analysis related to processes critical for early folliculogenesis.
The resulting annotations are then used as a basis for functional data mining including metabolic reconstruction.
The benefit of having a genome sequence is that it provides a basis for functional genomics.
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