Sentence examples for basis for extrapolation of from inspiring English sources
The generated data indicate comparable kinetic properties of pig and minipig AChE and may provide a kinetic basis for extrapolation of data from pig studies to humans.
Climatological analyses are required to convert information gathered at a dispersed network of weather stations into more relevant forms (radiation, dew point, vapor pressure deficit) and to provide the basis for extrapolation of climatic variation across landscapes.
Provide information about the mode of action (MOA) of chemicals, i.e. the mechanism of toxicity; in turn, reducing the uncertainties involved in chemical risk assessment by providing, for example, a basis for extrapolation of the effects across species.
A validated laboratory marker of clinical protection would provide a robust basis for extrapolation of clinical efficacy data derived in specific settings to other regions or populations.
By adding this information to the current PBPK model, together with quantitative information on the transporter expression levels in animals and humans, the PBPK model will serve as a basis for extrapolation of preclinical findings and ultimately only in vitro determinations of physicochemical properties of drugs, to the human situation.
However, the availability of high-quality country-level data on 2 major host risk factors for iNTS (i.e., HIV and malaria [ 6 ]) provides a basis for extrapolation of the few population-based iNTS surveillance data that are available for other areas.
Equally, studies in only one species are a weak basis for extrapolation to humans because an absence of effects in one species does not mean that effects will not be seen in another species.
Long-term behaviour and effectiveness of installed mass spring systems in S-Bahn tunnels were reviewed and served as a basis for extrapolation for newer developments under other conditions.
Such information, used in conjunction with that obtained from other preclinical studies, can then form a reasonably sound basis for extrapolation to man.
The laboratory trials then serve as a basis for the extrapolation of findings of controlled laboratory studies to effects that may be observable in free-ranging species.
On the basis of extrapolation of recommendations established for hemorrhagic shock in trauma patients [87], but also for septic shock [88], a mean blood pressure of approximately 65 mmHg can be proposed.
