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These new single-digit nanomolar leads provide the basis for developing potent, novel Mps1 inhibitors with improved drug-like properties.
The lead peptide-inhibitor, 6a, with high potency and good binding profile can be used as the basis for developing potent small molecule inhibitors against MDR variants of HIV.
The information has the potential to be used as the basis for developing potent and subtype-selective inhibitors of receptor- and chemically activated Ca2+ entry mechanisms, for which currently used inhibitors are inadequate.
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These results represent a promising starting point for developing potent small molecule RORγ inhibitors.
These results may provide deep insight into potential structural modifications for developing potent c-Met inhibitors.
Understanding of the interaction between FABP4 and inhibitors will be helpful in developing potent FABP4 inhibitors for cancer therapy.
What is the theoretical basis for developing reading scales?
The gasification designs developed could form the basis for developing an integrated UCG model.
This became the basis for developing a momentum day trading strategy.
These dimensions formed the basis for developing the questionnaire.
This database formed the basis for developing the sampling framework.
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