Sentence examples for basis for alterations from inspiring English sources

Signaling by AIs in the QS system forms the basis for alterations in various gene expressions including virulence factors, secretion system, motility, sporulation, and biofilm formation [ 29].

Although the mechanistic basis for alterations in miRNA, especially in the context of cellular malfunction, is not well understood, such alterations play a pivotal role in pathological processes and have recently been proposed as biomarkers for brain neoplasms, degenerative diseases, autism, and schizophrenia [ 23– 25].

Although at the present time it is unclear whether the altered gene expression resulted in permanent alterations, the gene targets and molecular pathways identified at 72 hpf support a molecular basis for alterations of neurite growth and synapse formation and function that have been observed in previous studies.

Although the basis for alteration in body weight is not clear, it may be related to changes in overall metabolism, potentially including tankyrase-dependent regulation of GSV.

Doing so requires consideration of the biological basis for alteration of normal hormonal function and how this varies among species.

These observations provide new insight into the molecular basis for the alterations in neurite outgrowth and axonal viability associated with the CMT disease state.

Thus, SFR may explain the mechanistic basis for unexpected alterations in cellular signaling, for example, due to gain or loss-of-function mutations found in human diseases [11], [12].

Because epigenetic changes can alter whole-genome expression profiles of various cell types that constitute different tissues and organs, these modifications provide plausible basis for transcriptomic alterations that are associated with various diseases [4], [5].

To examine the cellular basis for these alterations in bone, we examined the impact of combined Pkd1 and Kif3a deficiency on cell proliferation, osteoblastic differentiation, and gene expression profiles in cells isolated from calvaria of newborn wild-type, single heterozygous and compound heterozygous Pkd1 and Kif3a deficient mice (Fig. 3).

Therefore, these changes are the basis for important alterations linked to aging [ 11- 15].

Increased expression of Fas receptor and lower levels of sFas may provide the basis for these alterations that in turn may promote the rupture of tendons.